Human PYY (3-36) Specific RIA Kit
All components are included in each kit (standards, antibody, tracer, quality controls, matrix,
precipitating reagent, and buffer) to complete a RIA.
Peptide YY (PYY), a novel 36 amino-acid amidated hormone is a component of the complex neuroendocrine control process . This gut hormone (fragment 3-36), when infused into subjects, has been shown to reduce food intake in normal weight and obese individuals. PYY (3-36) infusion also reduces the plasma levels of the hunger - promoting hormone ghrelin . PYY (3-36) levels have been shown to drop pre-meal and then increase post prandially. In circulation , PYY (3-36) exists in at least two molecular forms: (1-36) and (3-36).
LINCO’s PYY (3-36) radioimmunoassay (RIA) kit utilizes an antibody, which is specific for PYY (3-36) with no measurable crossreactivity to PYY (1-36). The PYY (3-36) kit is suitable for measurement of PYY (3-36) in human serum, plasma, or tissue culture media.
ASSAY CONDITIONS: Two-day, disequilibrium assay, incubation at 4°C
Sample volume: 100 μL serum, plasma, or tissue culture sample
STANDARD CURVE RANGE: 20 - 1280 pg/mL
SENSITIVITY IN TISSUE CULTURE/SERUM/PLASMA: 20 pg/mL
LABEL: 125I-PYY
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